Naloxone is an opioid antagonist medicine that works to reverse an opioid overdose. The medication comes in two primary forms, nasal spray, and injectable Naloxone. It can only be used to reverse opioid overdoses such as oxycontin, fentanyl, methadone, vicodin, and Heroin. Naloxone will not reverse an overdose resulting from non-opioid drugs, like cocaine, benzodiazepines, or alcohol. Administering Naloxone to a non-opioid overdose victim will not harm them, it is safe. An additional dose of Naloxone can be administered every 2-3 minutes if an overdose victim is continuing to not respond. Narcan is the brand name for Naloxone.